Monsters vs. Aliens
Susan Murphy is hit by a meteorite on her wedding day and grows to forty-nine foot eleven, becoming Ginormica. The biggest-budget giantess protagonist there has ever been, and played entirely straight as a heroine.Worth watching: The wedding, and the San Francisco fight.
IMDb Wikipedia
Giantess Female Growth Instant Growth Alien & Cosmic Classic Giantess Keeping & Caretaking City Destruction